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PI-RADS
PI-RADS 1: very low (clinically significant cancer is highly unlikely to be present)
PI-RADS 2: low (clinically significant cancer is unlikely to be present)
PI-RADS 3: intermediate (the presence of clinically significant cancer is equivocal)
PI-RADS 4: high (clinically significant cancer is likely to be present)
PI-RADS 5: very high (clinically significant cancer is highly likely to be present)
T2-weighted imaging
Peripheral zone (PZ)
1: uniform high signal intensity (SI)
2: linear or wedge shaped hypointensity or diffuse mild hypointensity, usually indistinct margin
3: heterogeneous signal intensity or non-circumscribed, rounded, moderate hypointensity; includes others that do not qualify as 2, 4, or 5
4: circumscribed, homogenous moderately hypointense focus or mass confined to prostate and <1.5cm in the greatest dimension
5: same as 4 but ≥1.5 cm in greatest dimension or definite extraprostatic extension/invasive behavior
Transition zone (TZ)
1: homogenous intermediate signal intensity
2: circumscribed hypointense or heterogeneous encapsulated nodule(s) (BPH)
3: heterogeneous signal intensity with obscured margins. Includes others that do no qualify as 2, 4, or 5
4: lenticular or non-circumscribed, homogenous moderately hypointense, and <1.5cm in greatest dimension
5: same as 4, but ≥1.5cm in greatest dimension or definite extraprostatic extension/invasive behavior
Diffusion weighted imaging (DWI)
1: no abnormality and ADC and high b-value DWI
2: indistinct hypointense on ADC
3: focal mildly/moderately hypointense on ADC and isointense/mildly hyperintense on high b-value DWI
4: focal markedly hypointense on ADC hyperintense on high b-value DWI; <1.5cm in greatest dimension
5: same as 4 but ≥1.5cm in greatest dimension or definite extraprostatic extension/invasive behavior
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